View abstract. Laugharne, J. D., Mellor, J. E., and Peet, M. Fatty acids and schizophrenia. Cameron, M., Gagnier, J. J., Little, C. V., Parsons, T. J., Blumle, A., and Chrubasik, S. Evidence of effectiveness of herbal medicinal products in the treatment of arthritis. The hypotensive effect of dietary gamma-linolenic acid and associated alterations in tissue fatty acid composition and the Renin-Angiotensin system. 2012;27(3):16-17. The Cochrane review notes that EPO may not be safe in the long run. Final report of a therapeutic trial. Joy, C. B., Mumby-Croft, R., and Joy, L. A. Polyunsaturated fatty acid (fish or evening primrose oil) for schizophrenia. Liang XC and Guo SS. Field, E. J. and Joyce, G. Effect of prolonged ingestion of gamma-linolenate by MS patients. Effect of dietary supplementation with linoleic and gammalinolenic acids on the pressor response to angiotensin II--possible role in pregnancy induced hypertension? View abstract. Cochrane Database Sys Rev 2010 2010;11:CD001123. Most women use either over-the-counter (OTC) pain relievers or home remedies. View abstract. View abstract. In her daily life, Ms. Picincu provides digital marketing consulting and copywriting services as well as nutrition counseling. View abstract. 2020;34(10):2628-2638. J Fam.Pract. A review published in Cochrane in April 2013 analyzed 27 studies assessing the benefits of EPO in eczema treatment. View abstract. Pellegrina, C. D., Padovani, G., Mainente, F., Zoccatelli, G., Bissoli, G., Mosconi, S., Veneri, G., Peruffo, A., Andrighetto, G., Rizzi, C., and Chignola, R. Anti-tumour potential of a gallic acid-containing phenolic fraction from Oenothera biennis. Side effects of evening primrose oil Short-term use of EPO has been shown to be safe. Wade, V. A., Mansfield, P. R., and McDonald, P. J. Takwale A, Tan E, Agarwal S, et al. Sture, G. H. and Lloyd, D. H. Canine atopic disease: therapeutic use of an evening primrose oil and fish oil combination. Centre for Reviews and Dissemination. A double-blind placebo controlled trial of Efamol Marine on skin and joint symptoms of psoriatic arthritis. Asthma. Pruthi S, Wahner-Roedler DL, Torkelson CJ, Cha SS, Thicke LS, Hazelton JH, and Bauer BA. View abstract. View abstract. 1999;13(7):627-629. Engler, M. M., Schambelan, M., Engler, M. B., Ball, D. L., and Goodfriend, T. L. Effects of dietary gamma-linolenic acid on blood pressure and adrenal angiotensin receptors in hypertensive rats. View abstract. 1. Diabet Med 1990;7(4):319-323. Researchers believe that it may be due to the hormonal changes occurring during the menstrual cycle. Contact Lens Spectrum 2009;24(7):14-15. Jenkins AP, Green AT, and Thompson RP. Evening primrose oil benefits are said to include everything from PMS relief to better cardiovascular health. Jamilian M, Karamali M, ,Taghizadeh M, et al. View abstract. Vaddadi KS. View abstract. Menendez JA, del Mar Barbacid M, Montero S, et al. Clin Rheumatol 1989;8(2):238-244. Rezapour-Firouzi S, Arefhosseini SR, Mehdi F, et al. A 20-year-old male asked: does taking evening primrose oil capsulesdaily cause side effects like reduced testosterone levels? 1998;98(3):285-292. Arisaka, M., Arisaka, O., and Yamashiro, Y. Fatty acid and prostaglandin metabolism in children with diabetes mellitus. A double- blind placebo controlled trial. Dietary gamma-linolenic acid lowers blood pressure and alters aortic reactivity and cholesterol metabolism in hypertension. Greaves, M. W. and Corbett, M. F. Treatment of atopic eczema with evening primrose oil. Am J Med 12-19-2005;118 Suppl 12B:98-108. Control Clin Trials 1996;17:60-8. View abstract. Ring, J. and Kleinheinz, A. Mansel RE, Pye JK, and Hughes LE. D'Almeida A, Carter JP, Anatol A, Prost C. Effects of a combination of evening primrose oil (gamma linolenic acid) and fish oil (eicosapentaenoic + docahexaenoic acid) versus magnesium, and versus placebo in preventing pre-eclampsia. Effects of altering dietary essential fatty acids on requirements for non-steroidal anti-inflammatory drugs in patients with rheumatoid arthritis: A double blind placebo controlled study. Journal of Holistic Medicine. Wolkin, A., Jordan, B., Peselow, E., Rubinstein, M., and Rotrosen, J. Soulairac, A., Lambinet, H., and Neuman, J. C. [Schizophrenia and prostaglandins. 2008;74(5):447-452. Journal of Dermatological Treatment 1993;4:33-36. 2009;58(10):552-559. Atherosclerosis 1990;81:199-208. Corbett R, Meagher F, and Leonard B. View abstract. Haslett C, Douglas JG, Chalmers SR, Weighhill A, and Munro JF. Med Hypotheses 1988;25(4):189-195. Effect of evening primrose oil supplementation on lipid profile: a systematic review and meta-analysis of randomized clinical trials. Online ahead of print. Langmead, L., Chitnis, M., and Rampton, D. S. Use of complementary therapies by patients with IBD may indicate psychosocial distress. Dr. Ed Friedlander answered. View abstract. The Medicines Control Agency (MCA), Epogam and Efamast (gamolenic acid) - withdrawal of marketing authorizations. Topical gamma-linolenic acid therapy in atopic dermatitis: a clinical and biometric evaluation. Interactions between essential fatty acids and steroid hormones. Menopause. Engler, M. M. Comparative study of diets enriched with evening primrose, black currant, borage or fungal oils on blood pressure and pressor responses in spontaneously hypertensive rats. In: Mansel RE (ed). Most of the time it happens because the dose is too high. View abstract. Ty-Torredes KA. Swapan S, Sabyasachi B Nath GD. 6-15-1989;129(5):381-388. Chenoy R, Hussain S, Tayob Y, et al. Gibson RA. Prostaglandin Leukkot Essent Fatty Acids 1992;45:33-36. New York: Wiley-Liss;1990. View abstract. Recent Developments in the Study of Benign Breast Disease. Neurol.Res 2008;30(7):710-719. But this combination might reduce the rate of swelling (edema). J Clin Immunol 2002;22:83-91. The effect of oral evening primrose oil on bishop score and cervical length amongst term gravidas. 1998;218(3):234-237. Evening primrose oil is effective in atopic dermatitis: a randomized placebo-controlled trial. Early research shows that taking 4.8 grams of evening primrose per day for 12 weeks does not add to the weight loss achieved with a reduced calorie diet in obese women. View abstract. J Agric.Food Chem 9-22-2010;58(18):9960-9966. Cochrane Database Sys Rev 2012;(1):CD009560. Therefore, always take evening primrose oil with food to avoid upset stomachs and other gastrointestinal side-effects. View abstract. Carter, J. and Verhoef, M. J. Efficacy of self-help and alternative treatments of premenstrual syndrome. 2012;3, Centre for Reviews and Dissemination. Huntley, A. L. and Ernst, E. A systematic review of herbal medicinal products for the treatment of menopausal symptoms. View abstract. Polyunsaturated fatty acid levels in premenstrual syndrome and the effect of dietary supplementation on symptoms. ).Some health conditions may make you more susceptible to the side-effects of the drug. The risks are even greater for pregnant women who use this remedy to reduce labor time. Hosp Pharm 1996;31:1553-4. Drug companies' evidence to justify advertising. View abstract. View abstract. Behan PO, Behan WM, Horrobin D. Effect of high doses of essential fatty acids on the postviral fatigue syndrome. 2003;188(5 Suppl):S56-S65. Schizophrenia. Horrobin, D. F. Lipids and schizophrenia. View abstract. View abstract. Br J Dermatol 1989;121:75-90. View abstract. Gamma linolenic acid with tamoxifen as primary therapy in breast cancer. Lancet 1985;2:373-7. The use of Evening Primrose Oil is … View abstract. View abstract. Health Technol Assess 2000;4(37):1-191. Side effects of taking evening primrose oil may include headaches and mild stomach upset. Soeken, K. L., Miller, S. A., and Ernst, E. Herbal medicines for the treatment of rheumatoid arthritis: a systematic review. 1981;3(2):118-139. Dry eye. Berth-Jones, J., Thompson, J., and Graham-Brown, R. A. Veale DJ, Torley HI, Richards IM, O'Dowd A, Fitzsimons C, Belch JJ, and Sturrock RD. Kiehl R, Ionescu G, Manuel P, and et al. Saied GM, Kamel RM, and Dessouki N. Low intensity laser therapy is comparable to bromocriptine-evening primrose oil for the treatment of cyclical mastalgia in Egyptian females. View abstract. According to the National Institutes of Health (NIH), current evidence doesn't support the use of EPO for any disease or health concern. 1998;36(7):363-366. [Evening primrose oil in neurodermatitis?]. The etiopathogenesis of premenstrual syndrome as a consequence of altered blood rheology: a new hypothesis. Bordoni, A., Biagi, P. L., Turchetto, E., Serroni, P., De Jaco, A. P., and Orlandi, C. [Treatment of premenstrual syndrome with essential fatty acids (evening primrose oil)]. Prostaglandins Leukot Essent Fatty Acids 1990;40:199-202. The following doses have been studied in scientific research: BY MOUTH: Have you ever purchased EVENING PRIMROSE OIL? Dove D, Johnson P. Oral evening primrose oil: its effect on length of pregnancy and selected intrapartum outcomes in low-risk nulliparous women (abstract). Dietary supplement interactions with antiretrovirals: a systematic review. Ferreira MJ, Fiadeiro T Silva M Soares AP. Clinical and experimental study on the long-term effect of dietary gamma-linolenic acid on plasma lipids, platelet aggregation, thromboxane formation, and prostacyclin production. [Clinical trial of a topical preparation containing urea, sunflower oil, evening primrose oil, wheat germ oil and sodium pyruvate, in several hyperkeratotic skin conditions]. Proc Nutr Soc Aust 1985;10:196. Taylor, M. Botanicals: medicines and menopause. 2012;3, Centre for Reviews and Dissemination. What factors influenced or will influence your purchase? A double-blind controlled trial of gammalinolenic acid (GLA) in the management of pre-menstrual gastrointestinal symptoms. Oenothera (Evening primrose oil, Fever plant, Sun drops) is an herbal supplement used for its anti-inflammatory and pain-relieving effects. 1988;7(1):S189. Cancelo Hidalgo MJ, Castelo-Branco C, Blumel JE, Lanchares Perez J.L, and Alvarez De Los Heros JI. Acids ( EFA ) and a BA in Psychology and a placebo-controlled trial hyperlipemia with primrose. Martini, I learn its uses and side-effects when treating rheumatoid arthritis rational basis for?! This copyrighted material is provided by natural medicines, see natural medicines Comprehensive Database it! The material appearing on LIVESTRONG.COM side effects of evening primrose oil for educational use only S. atopic dermatitis a! 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